Cardiovascular events related to ischemic coronary diseases are among the leading causes of death in the world. The most common of these diseases are in the diagnosis group called acute coronary syndromes (ACS). According to the 2012 data of the World Health Organization (WHO), Ischemic Heart Disease, stroke with 7.4 million people, and 6.7 million people and 3.1 people with Chronic Obstructive Pulmonary Disease (COPD). Cardiac Troponins (cTn) are very sensitive and specific indicators of myocardial damage in cardiac markers.It is included in the group of Cardiac Troponins, Troponin T (cTnT) and Troponin I (cTnI). In ACS, increased cTn levels are important in terms of both prognosis and treatment. In international algorithms, they are accepted as standard markers in the diagnosis and treatment of ACS. In many studies, cTn elevation was found to have negative prognostic value in the short-term, with or without myocardial infarction (MI), in patients hospitalized in the hospital intensive care unit. However, the level of cTn in the blood can increase even due to ischemic coronary diseases and even for non-cardiac reasons. Acute Coronary Syndrome occurs as a result of impaired integrity of the atherosclerotic plaque in the coronary vessel. The clot formed on the plaque impairs various degrees of coronary blood flow. In addition to the clot, different degrees of coronary spasm may accompany the picture. As a result of these changes, acute elevation myocardial infarction (STEMI), ST elevation acute myocardial infarction (NSTEMI) or unstable angina pectoris (Unstable Angina Pectoris, UAP) may occur in the clinic.
Keywords: Troponin; Heart failure; Unstable angina
Introduction
Cardiovascular events related to ischemic coronary diseases are the leading causes of death in the world [1]. Those who complain about ischemic coronary disease often apply to emergency departments for initial diagnosis and treatments. The most common of these diseases are in the diagnosis group called acute coronary syndromes (ACS) [2]. An approach principle consisting of clinical history, ECG and cardiac markers is used in the diagnosis of ACS's emergency department. Although the history and ECG elements of the clinical approach have the same characteristics since the past, cardiac markers have been frequently changed in recent years, and they continue to take place in diagnostic approaches by updating and updating them.
Among the cardiac markers, cardiac Troponins (cTn) are highly sensitive and specific indicators of myocardial damage. It is included in the group of Cardiac Troponins, Troponin T (cTnT) and Troponin I (cTnI). In ACS, increased cTn levels are important in terms of both prognosis and treatment [3]. In international algorithms, they are accepted as standard markers in the diagnosis and treatment of ACS [4,5]. In many studies, the height of cTn was found to have negative prognostic value in the short-term, with or without myocardial infarction (MI), in patients hospitalized in the hospital intensive care unit. However, the level of cTn in the blood can increase even without ischemic coronary diseases [6]. The number of clinical studies conducted on the increase of the level of cTn in the blood when it is not related to ischemic coronary diseases is low.
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