Ozone Therapy in the Treatment of Symptoms Associated to Trigeminal Neuralgia by Roxana Mirica in Open access Journal of Biogenerc Science and Research
Abstract
Background
Trigeminal neuralgia: Manifests as an extremely intense neuropathic pain that affects the patient’s life in all its aspects. The classical -according to the guides -treatment with Carbamazepine has various adverse reactions. Patients have a low compliance too, and stop the treatment. Analgesia through acupuncture was thoroughly studied in the meta-analysis conducted by Vickers et al. on 20,827 patients in 2017. We propose ozone therapy on trigger points as treatment, the antialgic effect of acupuncture being doubled with the trophic effect of the oxygen. Treatment, the antialgic effect of acupuncture being doubled with the trophic effect of the oxygen.Measures: A 54 years old patient with hemicrania and hypersensitivity on the right side of the face, who spoke with his mouth almost closed, after 12 sessions of ozone therapy, felt no pain, the symptoms were significantly improved.
Intervention: For an objective assessment of the treatment effect, we used VAS (Visual Analog Scale). Patients’ compliance to pain assessment is low, but the person feeling it is the only one who can accurately assess its intensity. Outcomes: Ozone is used in chronic diseases, in treating pain and for rejuvenation purposes, by injections, insufflations, autohemotransfusion and locally applied. Conclusion: Ozone therapy could be a first line treatment in trigeminal neuralgia, because it has no adverse effects, relief pain and increase quality of life of the patients.
Keywords: Pain; Trigeminal neuralgia; Ozone; Trigger points; Acupuncture; VAS scale
Introduction
Trigeminal neuralgia includes a complex of painful, intensely explosive (electric shock-like) manifestation in the oral and maxillofacialarea, sometimes accompanied by sweating or local hypersensitivity. The patient’s quality of life decreases dramatically as the pain is often debilitating and becomes chronic if left untreated. The “trigeminal” pain is a complex response from the body to certain stimuli, sometimes generated by inflammation along the trigeminal nerve route (fifth cranial nerve)or its branches (ophthalmic, maxillary, mandibular) [1] (Figure 1). This is a neuropathic, intense, explosive, repetitive and severe pain that lasts a few minutes [2], with a re-entry mechanism that causes enhancement of the sensorial perception. It is virtually a vicious circle.
In 2017, Kesand Matovina classified trigeminal neuralgia in 3 categories:
Classical (continued paroxistic pain). Secondary (associated with other neurological diseases or cerebral space replacement formations) Idiopathic [2]. Secondary trigeminal neuralgia with an identifiable cause is rare. The primary idiopathic form is the most common. The trigeminal neuralgia prevalence in the global population is 4/100,000 inhabitants, higher among women aged >50[1/2].The treatment for trigeminal neuralgia includes analgesic, anti-inflammatory, anticonvulsant medication (Carbamazepine, the treatment of choice according to the European guidelines), antidepressant medications, surgical treatment for nerve branch isolation or even sectioning thereof. Based on our real-world setting observations, acupuncture treatmentsor ozone therapiesare highly likely to cure the patient, especially in idiopathic, recent onset cases (less than 6 months).
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