Antigen and antibody for Coronavirus RNA Vaccination Development by Manu Mitra in
Coronavirus and its strains are associated to the subfamily of Orthocoronavirinae. It is associated with the family of Coronaviridae and order of Nidovirales and realm in Ribavirin. These are enveloped viruses with positive single stranded RNA genome and nucleocapsid of helical symmetry. The size of genome for coronaviruses varies from 27 to 34 kilobases.
Mutation of Coronavirus may or may not be recognized by the immune system on subsequent infection; and once it highjacks host of the cell, replication of virus becomes faster. As a result immune system will be unable to recognize the strains of these infections; infections caused by coronavirus like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) have inclined to be very severe and can cause significant mortality. In this paper discusses about antigen and antibody for development of vaccines for coronavirus and its strains so that some of the B cells become memory B cells which recognizes future exposure to the disease.
Coronavirus was discovered in the year 1960’s. It infected in chicken and two human patients with common cold. There are family of corona virus which is as lethal as Severe Acute Respiratory Syndrome (SARS). Most of these involves respiratory tract infections [1]. There are many human coronaviruses to exist. Few them are human coronavirus 229E (HCoV-229E), HCoV-OC43 which is related coronavirus (SARA-Cov). The genome structure of coronavirus has unique features that includes N-terminal fragment within spike protein [2]. A new strain of corona virus which was discovered in December 2019 named as COVID 19.
https://biogenericpublishers.com/pdf/JBGSR-RW-01-2020.pdf
https://biogenericpublishers.com/jbgsr-rw-01-2020-text/
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Mutation of Coronavirus may or may not be recognized by the immune system on subsequent infection; and once it highjacks host of the cell, replication of virus becomes faster. As a result immune system will be unable to recognize the strains of these infections; infections caused by coronavirus like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) have inclined to be very severe and can cause significant mortality. In this paper discusses about antigen and antibody for development of vaccines for coronavirus and its strains so that some of the B cells become memory B cells which recognizes future exposure to the disease.
Coronavirus was discovered in the year 1960’s. It infected in chicken and two human patients with common cold. There are family of corona virus which is as lethal as Severe Acute Respiratory Syndrome (SARS). Most of these involves respiratory tract infections [1]. There are many human coronaviruses to exist. Few them are human coronavirus 229E (HCoV-229E), HCoV-OC43 which is related coronavirus (SARA-Cov). The genome structure of coronavirus has unique features that includes N-terminal fragment within spike protein [2]. A new strain of corona virus which was discovered in December 2019 named as COVID 19.
https://biogenericpublishers.com/pdf/JBGSR-RW-01-2020.pdf
https://biogenericpublishers.com/jbgsr-rw-01-2020-text/
To Know more Open access publishers Click on Biogeneric publishers
https://biogenericpublishers.com/
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